Agence Deborah Druba
AGENCE DEBORAH DRUBA is an international rights agency based in Paris.
View Rights PortalAGENCE DEBORAH DRUBA is an international rights agency based in Paris.
View Rights PortalThis is the first study to examine the entire life cycle in the Middle Ages. Drawing on a wide range of secondary and primary material, the book explores the timing and experiences of infancy, childhood, adolescence and youth, adulthood, old age and, finally, death. It discusses attitudes towards ageing, rites of passage, age stereotypes in operation, and the means by which age was used as a form of social control, compelling individuals to work, govern, marry and pay taxes. The wide scope of the study allows contrasts and comparisons to be made across gender, social status and geographical location. It considers whether men and women experienced the ageing process in the same way, and examines the differences that can be discerned between northern and southern Europe. The fourteenth and fifteenth centuries suffered famine, warfare, plague and population collapse. This fascinating consideration of the life cycle adds a new dimension to the debate over continuity and change in a period of social and demographic upheaval.
This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. As well as studying the individual amino acids, including arginine, sulfur amino acids, branched-chain amino acids and aromatic amino acids, a number of themes are explored throughout the work. These include: - Comparative issues between the metabolism of microbes and those of higher organisms, including plants and mammals - Potential for drug targets in pathways of both biosynthesis and degradation of amino acids - Relationship between amino acids or associated enzymes and virulence in parasitic pathogens - Practical implications for food microbiology and pathogen characterization - Future priorities relating to fundamental biochemistry of microrganisms, food quality and safety, human and animal health, plant pathology, drug design and ecology As the volume of research into the metabolism of amino acids grows, this comprehensive study of the subject is a vital tool for researchers in the fields of biological, medical and veterinary sciences, including microbiology, biochemistry, genetics and pathology. This book is also essential for corporate organizations with active research and development programmes, such as those in the pharmaceutical industry. ; This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. ; -: PrefacePART I: GLUTAMATE1: Structural and Functional Properties of Glutamate Dehydrogenases2: Glutamate Decarboxylase in Bacteria3: The Yeast GABA ShuntPART II: LYSINE, ARGININE AND HYDROXYPROLINE4: Lysine Biosynthesis in Microorganisms5: Arginine Deiminase in Microorganisms6: Arginase and Microbial Pathogenesis in the Lungs7: Arginine and Methionine as Precursors of Polyamines in Trypanosomatids8: Ornithine and Lysine Decarboxylation in Bacteria9: The Role of Nitric Oxide Signalling in Yeast Stress Response and Cell Death10: Hydroxyproline Metabolism in MicroorganismsPART III: SERINE AND THREONINE11: Cellular Responses to Serine in Yeast12: Threonine Degradation in Hyperthermophilic OrganismsPART IV: SULFUR AMINO ACIDS13: Methionine Synthesis in Microbes14: Regulation of Sulfur Amino Acid Metabolism in Fungi15: Insight on O-Acetylserine Sulfhydrylase Structure, Function and Biopharmaceutical ApplicationsPART V: BRANCHED-CHAIN AMINO ACIDS16: Metabolic Engineering of Corynebacterium glutamicum for L-Valine Production17: Flavour Formation From Leucine by Lactic Acid BacteriaPART VI: AROMATIC AMINO ACIDS AND HISTIDINE18: Microbial Degradation of Phenolic Amino Acids19: The Biosynthesis of Tryptophan20: Tryptophan Biosynthesis in Bacteria: Drug Targets and Immunology21: The Kynurenine Pathway of Tryptophan Metabolism in Microorganisms22: Histidine Degradation in Bacteria23: Histidine Phosphatase Superfamily in Pathogenic BacteriaPART VII: D-AMINO ACIDS24: Functions and Metabolism of D-Amino Acids in Microorganisms25: Pathways of Utilization of D-Amino Acids in Higher OrganismsPART VIII: ECOLOGY26: Rhizobial Amino Acid Metabolism: Polyamine Biosynthesis and Functions27: Working Together: Amino Acid Biosynthesis in Endosymbiont-Harbouring Trypanosomatidae28: Amino Acid Metabolism in Helminths29: Microbial Degradation of Amino Acids in Anoxic Environments30: Utilization of N-Methylated Amino Acids by Bacteria31: Biofilm Formation: Amino Acid Biomarkers in Candida albicans32: Recent Advances Underpinning Innovative Strategies for the Future
Mit seinem Cthulu-Mythos wollte H. P. Lovecraft eine Atmosphäre kosmischen Grauens schaffen, die Archaisches mit den modernen Erkenntnissen der Wissenschaft verbindet und unserer Zeit angemessen ist. Die Angst hielt er für das älteste und stärkste Gefühl, mit dem er in seinen Erzählungen gerne spielte. Die besten Erzählungen von H. P. Lovecraft sind in diesem Rand zusammengefaßt.
Rucheng, Hunan, is the first large-scale centralized land recuperation after the Red Army's Long March. A story of "half-quilt" embodies the deep feelings of the military and civilians in the village of Shazhou in Rucheng. The revolutionaries Mao Zedong and Zhu De launched revolutionary activities in Rucheng, which has consolidated the mass foundation on this land.The book takes the "Half Quilt" story as the entrance, integrates the Long March story and revolution story of Rucheng, and the story of Shazhou Village's poverty eradication in the new era.
Peacemaking in the Middle Ages explores the making of peace in the late-twelfth and early thirteenth centuries based on the experiences of the kings of England and the kings of Denmark. From dealing with owing allegiance to powerful neighbours to conquering the 'barbarians', this book offers a vision of how relationships between rulers were regulated and maintained, and how rulers negotiated, resolved, avoided and enforced matters in dispute in a period before nation states and international law. This is the first full-length study in English of the principles and practice of peacemaking in the medieval period. Its findings have wider significance and applications, and numerous comparisons are drawn with the peacemaking activities of other western European rulers, in the medieval period and beyond. This book will appeal to scholars and students of medieval Europe, but also those with a more general interest in kingship, warfare, diplomacy and international relations.
This book explores the relationship between the papacy and reform against the backdrop of social and religious change in later tenth and eleventh-century Europe. Placing this relationship in the context of the debate about 'transformation', it reverses the recent trend among historians to emphasise the reform developments in the localities at the expense of those being undertaken in Rome. It focuses on how the papacy took an increasingly active part in shaping the direction of both its own reform and that of society, whose reform became an essential part of realising its objective of a free and independent Church. It also addresses the role of the Latin Church in western Europe around the year 1000, the historiography of reform, the significance of the 'Peace of God' as a reformist movement, the development of the papacy in the eleventh century, the changing attitudes towards simony, clerical marriage and lay investiture, reformist rhetoric aimed at the clergy, and how reformist writings sought to change the behaviour and expectations of the aristocracy. Summarising current literature while presenting a cogent and nuanced argument about the complex nature and development of reform, this book will be invaluable for an undergraduate and specialist audience alike.
This is the first study to examine the entire life cycle in the Middle Ages. Drawing on a wide range of secondary and primary material, the book explores the timing and experiences of infancy, childhood, adolescence and youth, adulthood, old age and, finally, death. It discusses attitudes towards ageing, rites of passage, age stereotypes in operation, and the means by which age was used as a form of social control, compelling individuals to work, govern, marry and pay taxes. The wide scope of the study allows contrasts and comparisons to be made across gender, social status and geographical location. It considers whether men and women experienced the ageing process in the same way, and examines the differences that can be discerned between northern and southern Europe. The fourteenth and fifteenth centuries suffered famine, warfare, plague and population collapse. This fascinating consideration of the life cycle adds a new dimension to the debate over continuity and change in a period of social and demographic upheaval.
Miss Bee and her friends are as busy as bees, because they are planning an extraordinary trip! They thought, designed, worked hard, and a little harder for a little longer… until they finally got everything they needed. They used every single help they can find to embark on an incredible journey; would you like to join them? A marvellous story of a little girl wanting to visit outer space, Miss Bee is intriguing as it is amusing. With its dynamic tone and alluring illustrations, Miss Bee’s story will keep your child’s attention until the very end
This critically aclaimed book, now in its second edition is firmly established as an essential guide to this recent historiographical debate. Adopted as a set book by the Open University. An indispensable guide to Marxist historiography for undergradu. . . . ;
The paperback release of this classic work.
Maher realizes one day he is an only child with no siblings. He starts to feel a bit lonely, and wishes he had siblings - like his friends and cousins. Luckily, his toys are here and now it’s time to show Maher what it means to be surrounded with brothers and sisters.It’s a heartwarming story that shows how rich and powerful the imagination of an only child can be.
You may be both different and the same as all the other children.This is what this book tackling the Down Syndrome explains, through the story of a child who just wants to be friends with everybody else.