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      • Trusted Partner
        Animal breeding
        December 2004

        Mammalian Genomics

        by Edited by Anatoly Ruvinsky, Jennifer A Marshall Graves

        Genomics has experienced a dramatic development during the last 15-20 years. Data from mammalian genomes such as the human, mouse and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow. This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion and lab animals. Topics covered include structural and functional aspects of the mammalian genome, mechanisms of genomic changes at the molecular level, evolution of DNA sequences, comparative chromosome mapping and painting, genome databases, gene prediction and the use of genomic information to understand inherited diseases. Contributors include leading researchers from Europe, USA, Australia and Japan.

      • Trusted Partner
        Genetics (non-medical)
        September 2002

        Quantitative Genetics, Genomics and Plant Breeding

        by Edited by Manjit S Kang

        This book provides an overview of the rapidly developing integration and interdependence of quantitative genetics, genomics, bioinformatics and their application to plant breeding. Chapters have been developed from a symposium held in Baton Rouge, Louisiana, in March 2001, although additional contributions have also been commissioned especially for this volume. The main topics covered include: quantitative trait loci (QTL) mapping, genomics, bioinformatics and marker-assisted selection; tissue culture and alien introgression for crop improvement; and advances in genotype by environment interaction/stability analysis.

      • Trusted Partner
        July 2023

        Linear Models for the Prediction of the Genetic Merit of Animals

        by Raphael A Mrode, Ivan Pocrnic

        The prediction of producing desirable traits in offspring such as increased growth rate, or superior meat, milk and wool production, is a vital economic tool to the animal scientist. Covering the fundamental principles of the application of linear models for the prediction of genetic merit in livestock, this new edition is fully updated to incorporate recent advances in methods of genomic prediction for pure and cross-bred animals. It provides models for the analysis of main production traits as well as functional traits, and includes numerous worked examples. The book covers: - models of survival analysis, social interaction and sire and dam models; - advancements in the use of SNPs in the computation of genomic breeding values; - single step approaches to genomics; - genomic non-additive models; - temporal and genomic analysis of genetic change. Suitable for postgraduate students, researchers and lecturers of animal breeding, genetics and genomics, this established textbook provides a thorough grounding in both the basics and new developments of linear models and animal genetics.

      • Trusted Partner
        July 2022

        Next-generation Sequencing and Agriculture

        by Philipp Bayer, David Edwards

        This book summarises the impacts that the genome sequencing revolution has had in all areas across animal and plant agriculture, including cattle, orphan crops, cash crops, and more, with reference to applications in many species and locations. It explains new techniques and their use in understanding epigenetics, breeding and conservation.

      • Trusted Partner
        June 2024

        Genetics of Salt Tolerance in Plants

        a Central Dogma Perspective and Strategies for Enhancement

        by Showkat Ahmad Ganie, Shabir Hussain Wani

        Gene expression in cells follows a prescribed pathway that conforms to the Central Dogma; where the genetic information stored in DNA is transcribed into RNA and then expressed into proteins, which influences most plant traits. Plant salt tolerance research is directed towards identifying nucleotide variants that could contribute to tolerant phenotypes. This book comprehensively presents the current state of knowledge on plant salt tolerance through meticulous analysis of the processes operating across the Central Dogma. It provides a detailed account of modulation of gene expression through genome editing systems to achieve crop improvement against salt stress. It also provides state-of-the-art information on advances in breeding technologies of genome selection and accelerated de novo domestication for rapidly improving the salt tolerance of plants for global food security. This book: 1.Provides a comprehensive coverage of plant salt tolerance mechanisms. 2.Spotlights various factors functioning along the Central Dogma pathway and their regulation in response to salinity. 3.Examines how these factors function to protect the plants from high salinity. 4.Highlights advances in cutting-edge breeding technologies for improving salt tolerance. The book will be of particular value to students and researchers of plant genetics, molecular biology and physiology and those with an interest in salinity and salt tolerance.

      • Trusted Partner
        Medicine
        July 2020

        Paratuberculosis

        Organism, Disease, Control

        by Marcel A Behr, Karen Stevenson, Vivek Kapur, Ali Thompson

        Paratuberculosis, also referred to as Johne's disease, affects cattle, goats, sheep, buffalo, deer and other ruminants. Examining the epidemiology of paratuberculosis, the organism that causes the disease, and practical aspects of its diagnosis and control, the book also addresses the link between paratuberculosis in the food chain and human health implications, including Crohn's disease. This timely new edition: - builds on a strong foundation to update, streamline and better structure existing chapters with important new developments from the last decade; - includes new chapters discussing the fast-growing field of whole genome based comparative genomics, and the increasing opportunities for disease control in low- and middle-income countries; - Brings on board rising star new authors from diverse backgrounds to include varied perspectives. A truly comprehensive, critical reference resource, this book is an essential reference for large animal veterinarians, livestock industry personnel and those involved in the dairy and meat industries, as well as microbiologists, researchers and students in these fields.

      • Trusted Partner
        Science & Mathematics
        September 2016

        Biotechnology of Major Cereals

        by Huw D Jones

        Biotechnology of Major Cereals will focus on the recent advances and future prospects in cereal biotechnology. The first part of the book will cover the world’s major cereals and focus on new developments and trends. The second part will be technology rather than species-led, detailing fundamental developments in technologies and significant target traits. ; In this book experts explain and discuss the latest biotechnological advances in cereal crop science, including the latest results of gene editing techniques ; 1: Biotechnology of Major Cereals 2: Genetic Transformation of Maize: Conventional Methods and Precision Genome Modification 3: Biotech Maize: Industry Development & Impact 4: Sorghum Genetic Transformation: Current Status and Future Target Traits 5: Barley as a Cereal Model for Biotechnology Applications 6: Wheat Biotechnology; Recent Developments and Future Trends 7: The Long and Winding Road of Rice Genetic Modification Technology and its Potential 8: Setaria Viridis; A Model for C4 Crop Biotechnology 9: Genome Editing in Cereals 10: Anther Culture for Doubled Haploids 11: Chloroplast Transformation in Cereals 12: Cross-species Silencing: Plant-mediated RNAi for Insect Control 13: Acrylamide in Cereals: The Problem and Potential Genetic and Agronomic Solutions 14: Engineering Cereal Endosperm 15: Key molecular and Metabolic Processes used for Genetic Engineering to Improve Freezing 16: Mergers and Acquisitions in Global Ag-Biotech

      • Trusted Partner
        January 2020

        Encephalitis, Second Edition

        by Alan Hecht D.C., Ona Bloom, and Jennifer Morgan

        Encephalitis is a brain inflammation that can come on suddenly and be fatal—is most commonly caused by a virus, but may also be the result of bacterial infection. Chapters include: Encephalitis Virus Human Genome Project (HGP) Immune System and Viral Infections Etiology of Encephalitis Glia Diagnosis and Treatment of Encephalitis Viral Encephalitis Prevention of Encephalitis

      • Trusted Partner
        September 2024

        Entomopathogenic Nematodes as Biological Control Agents

        by David I Shapiro-llan, Edwin Lewis, Steven P. Arthurs, Anil Baniya, Rubén Blanco-Pérez, Mary Barbercheck, Helge Bode, Raquel Campos Herrera, Julie G. Chacon-Orozco, Harun Cimen, Regina K. Cruzado Gutiérrez, Surendra K. Dara, Adler Dillman, Larry Duncan, Ioannis Eleftherianos, Shane Foye, Patrick Frettinger, Fernando Garcia-del-Pino, Itamar Glazer, John Goolsby, Dawn Gouge, Parwinder S Grewal, Richou Han, Sebnem Hazal Gulsen, Canan Hazir, Selcuk Hazir, Ivan Hiltpold, Ganpati B. Jagdale, Rinus Knoetze, Albrecht Koppenhofer, Gabriela Lankin, Luis Garrigós Leite, Diana Karime Londono, Antoinette P. Malan, Dana Ment, Jayashree Ramakrishnan, Gadi V P Reddy, Cesar Rodriguez-Saona, Weibin Ruan, Michael Samish, Ernesto San-Blas, Ramandeep Kaur Sandhi, Ana Luiza Sousa, Tatyana Stefanovska, Glen Stevens, S. Patricia Stock, Yoelvis Sulbaran, Ghada Tafesh-Edwards, Mustapha Touray, Stefan Toepfer, Derya Ulug, Bart Vandenbossche, Christopher Williams, Sheng-Yen Wu, Xun Yan

        Entomopathogenic nematodes (EPNs) are biocontrol agents that are used to control a wide variety of insect pests within agriculture and forestry. In addition to their use as bio-pesticides, EPNs have a fascinating biology and are thus considered model organisms in ecology, symbiosis and pathogenesis. This book presents basic knowledge and diverse applications to illustrate how EPNs play an important role as potent biocontrol solutions. It describes: Fundamental concepts such as biology, taxonomy, symbiosis genomics and behavioural ecology. Aspects of commercialization, including mass production, formulation, safety and regulation, and marketing. Diverse cropping systems e.g. maize, wheat and grains, citrus, orchard systems, berries, vine crops, vegetables and turf. Other applications including urban, nursery, forestry, greenhouse, veterinary and medical. Ecological considerations and applications in conservation biocontrol. This book is a must have for all pest management professionals including those practicing integrated pest management strategies.

      • Trusted Partner
        Medicine
        April 2018

        Bovine Tuberculosis

        by Mark Chambers, Stephen Gordon, Francisco Olea-Popelka, Paul Barrow

        This book is contemporary, topical and global in its approach, and provides an essential, comprehensive treatise on bovine tuberculosis and the bacterium that causes it, Mycobacterium bovis. Bovine tuberculosis remains a major cause of economic loss in cattle industries worldwide, exacerbated in some countries by the presence of a substantial wildlife reservoir. It is a major zoonosis, causing human infection through consumption of unpasteurised milk or by close contact with infected animals. Following a systematic approach, expert international authors cover epidemiology and the global situation; microbial virulence and pathogenesis; host responses to the pathogen; and diagnosis and control of the disease. Aimed at researchers and practising veterinarians, this book is essential for those needing comprehensive information on the pathogen and disease, and offers a summary of key information learned from human tuberculosis research. It will be useful to those studying the infection and for those responsible for controlling the disease.

      • Trusted Partner
        January 2020

        Biological Sciences, Revised Edition

        Notable Research and Discoveries

        by Kyle Kirkland, Ph.D.

        Biological Sciences, Revised Edition covers a wide range of topics under the vast umbrella of biology, the study of life. Students will learn about the methods and applications of the field through an exploration of disciplines, such as neurology, genetics, and virology. This newly revised edition uses scientific journal articles, reports, and press releases to offer the latest from key scientists and researchers in the field. Chapters include: Brain Imaging: Searching for Sites of Perception and Consciousness The Human Genome in Health and Disease Protein Structure and Function Biodiversity—The Complexity of Life The Biology and Evolution of Viruses Regeneration—Healing by Regrowing.

      • Trusted Partner
        September 2009

        Das Gen im Zeitalter der Postgenomik

        Eine wissenschaftshistorische Bestandsaufnahme

        by Staffan Müller-Wille, Hans-Jörg Rheinberger

        Seine Position als zentrales organisierendes Thema der Biologie des 20. Jahrhunderts verdankt ‚das Gen’ weniger endgültigen wissenschaftlichen Befunden als vielmehr der Tatsache, daß der ihm entsprechende Forschungsgegenstand, sein ‚epistemisches Objekt’ also, sich Zug um Zug instrumentell vermittelter, experimenteller Handhabung erschloß. Mit der Komplettierung der Sequenzen ganzer Genome, insbesondere des Humangenoms, ist die Genetik – als Wissenschaft ein Kind des 20. Jahrhunderts – erneut an den Rand eines grundlegenden Denkwandels getreten. Vielfach werden Stimmen laut, die den Genbegriff zu Gunsten systemischer Perspektiven in Frage stellen oder gar ganz aufgeben wollen. Auf der anderen Seite treten überwunden geglaubte Denkfiguren wie die Vererbung erworbener Eigenschaften oder die Einteilung des Menschen nach ‚Rassen’ wieder in das Blickfeld wissenschaftlicher und medizinischer Debatten. Um den Gegenwartshorizont des Genetischen angesichts dieser verwirrenden Situation abzustecken, ist eine historische Standortbestimmung angebracht. Es besteht kaum ein Zweifel daran, dass ‚das Gen’ das zentrale organisierende Thema der Biologie des 20. Jahrhunderts war. Ein Blick auf die Geschichte der Genetik und Molekularbiologie zeigt jedoch, dass es nie eine allseits akzeptierte Definition des Gens gegeben hat. Vielmehr befand sich der Begriff, und dies ist keineswegs untypisch für historisch einflußreiche wissenschaftliche Begriffe, immer im Fluß.

      • Trusted Partner
      • Trusted Partner
        December 2004

        Das Genom

        by Fischer, Ernst P

      • Trusted Partner
      • Trusted Partner
        January 1992

        Das Genom-Projekt

        Der genetische Bauplan des Menschen wird entziffert

        by Shapiro, Robert / Übersetzt von Kirchberger, Günther

      • Trusted Partner
        Biotechnology
        December 2004

        Plant Diversity and Evolution

        Genotypic and Phenotypic Variation in Higher Plants

        by Edited by Robert J Henry

        An understanding of plant diversity at both the genome and phenome level is important for both biodiversity conservation and plant breeding. Recent advances in genomics have also resulted in a growth of the subject of plant functional genomics. This book brings these areas together, by reviewing aspects of plant evolution as it relates to variation in plant genomes and associated variations in plant phenomes. Topics covered include chloroplast and mitochondrial genomes, reticulate evolution, polyploidy, population genetics within a species, the evolution of the flower, diversity in plant cell walls and in secondary metabolism, and the importance of plant diversity in ecology and agriculture.

      • Trusted Partner
        Epidemiology & medical statistics
        June 2013

        Genetic Epidemiology

        Methods and Applications

        by Melissa A Austin, Terri H Beaty, W David Dotson, Kelly Edwards, Stephanie M Fullerton, Marta Gwinn, Muin J Khoury, Barbara McKnight, Deborah Nickerson, Ruth Ottman, Bruce M Psaty, Stephen M Schwartz, John A Stamatoyannopolous, Janet L Stanford, Timothy A Thornton

        Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described. Concluding with a review of ethical issues and a framework for translating human genomics research to clinical practice and public health benefit, this textbook is an essential new resource for graduate students in epidemiology and public health genetics.

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