• Medicine
      January 2012

      EGFR Inhibitors in Cancer Treatment

      by Fortunato Ciardiello

      Epidermal growth factor receptor (EGFR) is a cell membrane receptor with tyrosine kinase activity that plays a crucial role in the control of key cellular transduction pathways in both normal and cancer cells. EGFR is over-expressed in a variety of human tumors, including head and neck, breast, lung and colorectal cancers – thus, it represents a relevant target for selective, molecularly targeted anticancer therapies. This book provide an overview of current knowledge on the use of EGFR inhibitors in cancer treatment, taking constant inspiration from the most recent advances reported in the scientific literature in order to define evidence-based guidelines for the oncology community.

    • Medicine
      March 2012

      Advances in the Treatment of B-Cell Chronic Lymphocytic Leukemia

      by Michael J Keating, Constantine Tam

      The past two decades have seen substantial advances in the understanding of chronic lymphocytic leukemia (CLL), including new insights from genetics and molecular biology regarding the heterogeneity in clinical behavior observed in this disease. The Editors highlight how vast and complex the CLL has become, but foresee a new dawn for physicians and researchers seeking to better understand and treat the disease. In reflecting on these advances, the eight chapters of this book from international experts address key issues in understanding CLL, its current management and future prospects for treatment. Topics include diagnosis & staging, genetics of disease, treatment options and chemotherapy, stem cell transplantation, options in refractory disease, prognostic factors and future directions for management.

    • Medicine
      January 2015

      Autism - A Handbook Of Diagnosis & Treatment Of Asd

      A Handbook Of Diagnosis And Treatement Of Asd

      by Sumita Bose

      Autism is a complex developmental disability. Generally, Autism presents itself during the first three years of a person's life. The condition has an effect on normal brain function characterized by social impairments, communication difficulties, and restricted, repetitive, and stereotyped patterns of behaviour. Males are five times more likely to be affected than females. As early as infancy, a baby with Autism may be unresponsive to people or focus intently on one item only. A child may appear to develop normally and then withdraw and become indifferent to social engagement. Children may fail to respond to their names and often avoid eye contact with other people. They have difficulty interpreting what others are thinking or feeling because they can't understand social cues. “Autism – A Handbook of Diagnosis & Treatment of ASD” discusses signs, symptoms, causes, myths, facts, therapies, treatment, education, career and many more things related to autism. It provides practical advice so that the special child can lead a quality life to the extent possible.

    • Medicine
      July 2015

      Practical Insulin, 4th Edition

      A Handbook for Prescribing Providers

      by American Diabetes Association

      The fourth edition of Practical Insulin: A Handbook for Prescribing Providers is a completely revised version of the popular ADA pocket reference. With information on all the currently FDA-approved insulins, this handy pocket guide gives you fast, reliable information and helps you overcome the challenges all clinicians face—choosing an insulin regimen to effectively manage blood glucose and patient resistance. It includes data on all types of insulin, mixing insulins, absorption rates, and more.

    • Medicine
      January 2016

      Clinical Care of the Diabetic Foot, 3rd Edition

      by David G. Armstrong, DPM, MD, PhD, and Lawrence A. Lavery, DPM, MPH, Editors

      The third edition of Clinical Care of the Diabetic Foot has been fully revised and updated, and continues to be the essential handbook on foot care and the treatment of the diabetic foot.The diabetic foot is typically the victim of nerve damage, micro- and macrovascular disease, and faulty healing, mechanisms that without proper care can lead to amputation. More than 80,000 diabetes-related amputations are performed in the United States each year, but non-specialist primary care providers, as well as residents, nurses, and diabetes educators, can help prevent this devastating, life-altering, and expensive complication. Healthcare professionals and medical students alike will find that this concise, well-indexed, and updated guide offers practical advice on detecting and managing diabetes-related foot complications.

    • Medicine

      American Diabetes Association Guide to Nutrition Therapy for Diabetes, 3rd Ed

      by Marion J. Franz, M.S., R.D., C.D.E., and Alison Evert, M.S., R.D., C.D.E.

      Nutrition therapy is an essential component of effective diabetes management. Healthcare providers need to stay current on new developments in nutrition therapy and specific interventions for a wide range of patient populations and special circumstances in order to provide the best possible outcomes for their patients. Revised and updated to incorporate the latest research and evidence-based guidelines, the third edition of the American Diabetes Association Guide to Nutrition Therapy for Diabetes is a comprehensiveresource for the successful implementation of nutrition therapy for people with diabetes.Topics covered include:• Macronutrients and micronutrients• Nutrition therapy for pregnant women, youth, older adults, andpeople with prediabetes• Nutrition therapy for hospitalized and long-term care patients• Celiac disease, eating disorders, and diabetes complications• Cost-effectiveness of nutrition therapy, health literacy and numeracy, and community-based diabetes prevention programs

    • Medicine
      August 2015

      Diabetes Case Studies

      Real Problems, Practical Solutions

      by Edited by Boris Draznin

      The "case study" approach is one of the most used and most effective formats to present medical information and is the foundation for developing evidence-based treatment protocols. Compiled and edited by one of the world's best known clinical endocrinologists, Boris Draznin, MD, PhD, Diabetes Case Studies offers more than 100 actual cases from leading diabetologists, outlining both typical and unusual diabetes cases. Each study will illustrate real life dilemmas with a discussion as to how the diagnostic and therapeutic approaches were selected and implemented, through a thorough, yet succinct, presentation of the problems, the diagnoses, treatment protocols, and results. Readers will have practical information to use when treating their diabetic patients.

    • Medicine
      August 2015

      Practical CGM

      Improving Patient Outcomes through Continuous Glucose Monitoring

      by Gary Scheiner

      Use of real-time continuous glucose monitors among people with type 1 and type 2 diabetes is growing rapidly and should continue to grow until an artificial pancreas is brought to market. Likewise, use of professional systems in healthcare practices is expanding. But, other than manufacturer instructional manuals and some book chapters on CGMs, there are no standalone publications available with concise, non-commercial instructions on CGM prescription and use.Additionally, continuous glucose monitors are too often not used to their full and proper potential. This leaves users with suboptimal glucose control and can result in system abandonment.To address this, diabetes educator and author Gary Scheiner has created Practical CGM: Improving Patient Outcomes through Continuous Glucose Monitoring to give healthcare providers the skill to make more effective use of the data generated by continuous glucose monitors, in both real-time and on a retrospective analytic basis. Using a plain-language approach and distilling content to concise, practical tips and techniques, Scheiner has created a guide that will help practitioners optimize patient use of CGM systems and, ultimately, improve glucose control and patient health outcomes.

    • Medicine
      July 2016

      Diabetes Risks from Prescription and Nonprescription Drugs

      Mechanisms and Approaches to Risk Reduction

      by Samuel Dagogo-Jack

      Over 29 million Americans have diabetes. Of those millions of people, the majority take at least one medication to treat their diabetes, but also take additional medications or supplements for other conditions. With this complex array of medications across such a broad and diverse population, potential contraindications are a real possibility. Diabetes Risks from Prescription and Nonprescription Drugs surveys the medication landscape and provides brief yet illuminating information on the potential effects any medication may have on people currently treating diabetes or whether any particular medication may increase the risk that someone will develop diabetes.Designed with the busy clinician in mind, Dr. Dagogo-Jack provides succinct descriptions of the drugs that may interact with diabetes medications or increase the risk of developing diabetes. He includes information from the latest clinical studies and the most recent literature to present a comprehensive, authoritative text on an elusive and troubling clinical conundrum.

    • Medicine
      December 2014

      Approaches to Behavior

      Changing the Dynamic Between Patients and Professionals in Diabetes Education

      by Janis Roszler and Wendy Rapaport

      Approaches to Behavior provides information and simple tools that healthcare professionals can use to help patients move beyond feelings that prevent them from benefiting fully from any learning opportunity. Each chapter opens with an introduction to experts’ newest psychological understanding about a common emotion. This is followed by a list of easy techniques healthcare professionals can employ with their patients. Each technique was contributed by experienced mental health experts who counsel people with diabetes. None of these techniques can take the place of the in-depth guidance mental healthcare professionals provide. Instead, this book is a first aid kit that experts can use to help patients start to move past strong emotions and become more receptive to vital information that will improve their lives and help them take control of their diabetes.

    • Medicine
      August 2014

      Diabetes Management in Long-Term Settings

      A Clinician's Guide to Optimal Care for the Elderly

      by Linda B. Haas, PhC, RN, CDE, and Sandra Drozdz Burke, PhD, ANP-BC, CDE, FAADE

      Diabetes Management in Long-Term Settings is a clinical guide for the treatment of elderly patients with diabetes. With the number of older adults growing exponentially and with a growing percentage of this group facing diabetic and prediabetic conditions, Diabetes Management in Long-Term Settings will help physicians, nurses, pharmacists, and administrators develop effective programs to care for this growing population. It is a practical clinical guide outlining the protocols of geriatric diabetes care and will be a sought-after reference for all clinicians.

    • Medicine
      August 2016

      Intensive Diabetes Management

      by Howard A. Wolpert

      Intensive diabetes management is the process by which blood glucose levels are closely controlled using multiple daily insulin injections or an insulin pump. People who use this method of diabetes management must be closely aligned with their health care team and highly motivated because it not only requires close scrutiny of blood glucose levels, but also constant monitoring of food intake and medication dosage, among other things.Although difficult to maintain, intensive diabetes management has proven very effective and is now the rule, rather than the exception, in diabetes care. Virtually all patients with diabetes—type 1 or type 2—can improve their glycemic control and overall health through intensive diabetes management.Intensive Diabetes Management is geared toward the health care practitioner who wants to implement this method in his or her patients. It emphasizes a team approach to patient care and offers guidance in helping patients move toward treatment goals appropriate for their individual skills and medical condition.Individual sections address all of the key topics in intensive diabetes management, including rationale/physiological Basis, team approach, education, pyschosocial issues patient selection/goals of therapy, insulin regimens, insulin pump therapy, monitoring, and nutrition management.This new edition is updated to cover the latest advances in medical research. New insights into diabetes and how they impact this particular treatment are covered. In addition, the data, guidelines, and procedures have been revised to reflect that newest positions of the American Diabetes Association's standards of care.

    • Medicine

      Meeting the American Diabetes Association Standards of Care, 2nd Ed

      An Algorithmic Approach to Clinical Care of the Diabetes Patient

      by Mayer B. Davidson, MD and Stanley H. Hsia, MD

      This book is an effective guide to improve the metrics (glycemic, lipid, blood pressure) of diabetes care. Using an algorithmic approach, you can improve patient outcomes. Drs. Davidson and Hsia provide documentation and evidence-based reasons to meet the glycemic, lipid, and blood pressure goals of the American Diabetes Association and background information for the drugs used to meet those outcome goals. In addition, based on the patient's response, the book describes what therapeutic changes need to be made to provide the most efficient and effective care for patients.

    • Medicine
      October 2017

      Complete Nurse's Guide to Diabetes Care, 3rd Edition *NEW* AVAILABLE OCTOBER 2017

      by Belinda P. Childs, ARNP, MN, BC-ADM; Marjorie Cypress, PhD, MSN, R, C-ANP, CDE; and Geralyn Spollett, MSN, C-ANP, CDE, editors

      Newly updated, Complete Nurse's Guide to Diabetes Care, 3rd edition, is the essential reference for nurses who work with diabetes patients. Get the latest details on the pertinent aspects of diabetes care and newest research, including: Fundamentals of diabetes care Special popuations Diseases and treatments that affect diabetes Diabetes care in the community

    • Medicine

      Annual Review of Diabetes 2017

      by American Diabetes Association

      Annual Review of Diabetes 2017 contains the American Diabetes Association's most current and important research. 44 articles taken from 2016 issues of Diabetes, Diabetes Care, Diabetes Spectrum, and Clinical Diabetes.

    • Medicine
      October 2015

      Biological Aspects of Suicidal Behavior

      by Kaschka, W.P., Kaschka, W.P., Rujescu, D., Gattaz, W.F.

      Suicide is one of the most important causes of death in modern societies. To develop more effective preventive measures, we have to be aware of and learn more about its neurobiological foundations. In recent years, the tools of modern neurosciences have increasingly been utilized to characterize the pathophysiology of complex human behaviors such as suicide. To improve suicide risk assessment and suicide prevention, a better understanding of its pathophysiology is crucial. This includes research from a variety of disciplines such as neuropsychological, psychosocial and cultural studies but also findings from biochemistry, neuropathology, electrophysiology, immunology, neuroimaging, genetics, and epigenetics. Important results have, for example, been obtained in the field of gene-environment interaction and suicidal behavior. We have just begun to understand how early-life adversity may increase suicide risk by epigenetic mechanisms. Based on such insights, novel therapeutic interventions and preventive measures can be developed. Furthermore, a better understanding of the pathophysiological mechanisms involved in suicidal behavior could reveal the mechanism of compounds like lithium salts. In this book, suicidal behavior and its prevention is discussed by international experts in the light of the most recent results from a broad spectrum of neurosciences.

    • Medicine
      July 2017

      Sleep-Related Breathing Disorders

      by Lin, H.-C., Bradley , P.J.

      Many sleep-related breathing disorders (SRBD), especially obstructive sleep apnea, originate from upper airway abnormalities. The connection to cardio- and cerebrovascular comorbidities is significant and the impact on the general health of patients is noteworthy. In recent years, important advances have been made in the research, diagnosis, and treatment of SRBD due to a multidisciplinary approach. This volume incorporates contributions in which the efforts and expertise of more than thirty outstanding experts are shared. It provides a concise, practical, and comprehensive review of sleep medicine and will enable researchers and physicians to stay updated on the latest developments.

    • Medicine
      September 2016

      Itch - Management in Clinical Practice

      by Szepietowski, J., Itin, P., Weisshaar, E., Jemec, G.B.E.

      Albeit a very common symptom in dermatology, internal medicine, psychosomatics, neurology, and even oncology, itching was under-researched up until 15 years ago. Since then, the clinical aspects of acute and chronic itch have been examined extensively. As a result, some books on the topic have become available. Whereas most publications focus on experimental aspects and diagnostics, this volume of the series 'Current Problems in Dermatology' provides a comprehensive overview regarding the management of chronic itch. Select authors consider interdisciplinary aspects as well as age, body region, and specific diseases as they present a great variety of available treatments. All physicians with patients suffering from itch – especially dermatologists, general practitioners, gerontologists, nephrologists, hepatologists, neurologists, and palliative care doctors – will find this publication to be an essential source of information.

    • Medicine
      June 2017

      Medical Retina

      Update 2017.

      by Bandello, F., Bandello, F., Querques, G., Corcóstegui, B., Loewenstein, A.

      In the 'ESASO Course Series' the essentials of the courses of the European School for Advanced Studies in Ophthalmology (ESASO) are made available to interested ophthalmologists, optometrists, technicians, and residents all over the world. In the seven years since the first edition of this book was published, major advances in diagnostics and management strategies of retinal diseases have evolved. This updated and revised edition takes this into account and focuses on the significant developments of preferred practice for diabetic retinopathy and dry and neovascular AMD. It further discusses pathology, imaging, and visualization of retinal diseases. In addition it considers biologic disease markers and new drugs being developed. Medical retina specialists who wish to stay abreast of the constantly changing world of medical retina will find this publication a must-read.

    • Medicine
      June 2016

      Sports Endocrinology

      by Lanfranco, F., Ghigo, E., Strasburger, C.J., Guaraldi, F.

      This book is an up-to-date, extensive overview of the effects of physical activity and training on endocrine function. It gives insights into a complex relationship by describing effects with respect to exercise performance, growth, development, and ageing. It includes discussions of the endocrine response depending on exercise mode, intensity, and duration as well as on gender, age, and fitness level. Additionally the book deals with the impact of environmental and psychological factors on endocrine level. A substantial part of Sports Endocrinology is devoted to the 'hot topic' of hormonal doping in sports. The properties of androgens, growth hormone, erythropoietin, and dietary supplements are highlighted. The use and abuse among professional and recreational athletes is discussed and specific methods of detection are presented and explained. All contributors are well-known experts in sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection, so this book is a must-read for every professional involved in the field.

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