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      • Trusted Partner
        Science & Mathematics
        March 2017

        The Handbook of Microbial Metabolism of Amino Acids

        by J P F D'Mello, K Abe, M I Afzal, M Akhtar, J M P Alves, R Balana Fouce, Q Bashir, R A Bender, Simon Brown, Catherine Cailliez-Grimal, R William Caldwell, Barbara Campanini, Yingying Cao, Trinad Chakraborty, D Charlier, N P Chowdhury, O O Coker, Daniela de Biase, Stephane Delaunay, Renwick C J Dobson, Mike F Dunn, D Fulton, Fabio Giovannercole, D E Holmes, A.O Hudson, Y Kera, G D Kornfeld, F Leroy, Z Liao, Rob D Locy, J S Lott, Patrick M Lucas, R Lucas, P Ludovico, J M Moran, A Mozzarelli, A J Nieuwkoop, N Osorio, John V Paietta, Prasit Palittapongarnpim, Emily J Parker, A Parthasarathy, F G Pearce, Eugenia Pennacchietti, Y Perez-Pertejo, R S Phillips, N Rashid, P J Quinn, F Rodrigues, M J Romero, B Sampaio-Marques, M A Savka, K Shibata, David C Simcock, H V Simpson, J A Smith, S Takahashi, Saleh Umair, X Wang, Matthew J Wargo, S Watanabe, Freya Wencker, W Ziebuhr, I W Dawes

        This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. As well as studying the individual amino acids, including arginine, sulfur amino acids, branched-chain amino acids and aromatic amino acids, a number of themes are explored throughout the work. These include: - Comparative issues between the metabolism of microbes and those of higher organisms, including plants and mammals - Potential for drug targets in pathways of both biosynthesis and degradation of amino acids - Relationship between amino acids or associated enzymes and virulence in parasitic pathogens - Practical implications for food microbiology and pathogen characterization - Future priorities relating to fundamental biochemistry of microrganisms, food quality and safety, human and animal health, plant pathology, drug design and ecology As the volume of research into the metabolism of amino acids grows, this comprehensive study of the subject is a vital tool for researchers in the fields of biological, medical and veterinary sciences, including microbiology, biochemistry, genetics and pathology. This book is also essential for corporate organizations with active research and development programmes, such as those in the pharmaceutical industry. ; This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. ; -: PrefacePART I: GLUTAMATE1: Structural and Functional Properties of Glutamate Dehydrogenases2: Glutamate Decarboxylase in Bacteria3: The Yeast GABA ShuntPART II: LYSINE, ARGININE AND HYDROXYPROLINE4: Lysine Biosynthesis in Microorganisms5: Arginine Deiminase in Microorganisms6: Arginase and Microbial Pathogenesis in the Lungs7: Arginine and Methionine as Precursors of Polyamines in Trypanosomatids8: Ornithine and Lysine Decarboxylation in Bacteria9: The Role of Nitric Oxide Signalling in Yeast Stress Response and Cell Death10: Hydroxyproline Metabolism in MicroorganismsPART III: SERINE AND THREONINE11: Cellular Responses to Serine in Yeast12: Threonine Degradation in Hyperthermophilic OrganismsPART IV: SULFUR AMINO ACIDS13: Methionine Synthesis in Microbes14: Regulation of Sulfur Amino Acid Metabolism in Fungi15: Insight on O-Acetylserine Sulfhydrylase Structure, Function and Biopharmaceutical ApplicationsPART V: BRANCHED-CHAIN AMINO ACIDS16: Metabolic Engineering of Corynebacterium glutamicum for L-Valine Production17: Flavour Formation From Leucine by Lactic Acid BacteriaPART VI: AROMATIC AMINO ACIDS AND HISTIDINE18: Microbial Degradation of Phenolic Amino Acids19: The Biosynthesis of Tryptophan20: Tryptophan Biosynthesis in Bacteria: Drug Targets and Immunology21: The Kynurenine Pathway of Tryptophan Metabolism in Microorganisms22: Histidine Degradation in Bacteria23: Histidine Phosphatase Superfamily in Pathogenic BacteriaPART VII: D-AMINO ACIDS24: Functions and Metabolism of D-Amino Acids in Microorganisms25: Pathways of Utilization of D-Amino Acids in Higher OrganismsPART VIII: ECOLOGY26: Rhizobial Amino Acid Metabolism: Polyamine Biosynthesis and Functions27: Working Together: Amino Acid Biosynthesis in Endosymbiont-Harbouring Trypanosomatidae28: Amino Acid Metabolism in Helminths29: Microbial Degradation of Amino Acids in Anoxic Environments30: Utilization of N-Methylated Amino Acids by Bacteria31: Biofilm Formation: Amino Acid Biomarkers in Candida albicans32: Recent Advances Underpinning Innovative Strategies for the Future

      • Trusted Partner
        Animal husbandry
        March 1998

        Energy Metabolism of Farm Animals

        by Edited by Kelvin J McCracken, E F Unsworth, A R G Wylie

        The Proceedings of the 14th Symposium on Energy Metabolism of Farm Animals, held in Northern Ireland in September 1997 comprises 85 original contributions by leading scientists from over 20 countries around the world. In keeping with previous Symposia in the series, held under the auspices of the European Association for Animal Production, this book contains papers which provide the latest research on the energy metabolism and other aspects of the physiology of a wide variety of farmed animals. Highlights include a comprehensive review of the current state of research on leptins and their potential applications in animal production, and a large section relating to organ and tissue metabolism, with major contributions from the USA, UK, France, Germany and Denmark. An important strength of the book is the diversity of species covered. For example, the sections on modelling and feed evaluation relate to pigs, sows, broiler chickens, laying hens, turkeys, lambs, beef and dairy cattle and fish. There are also substantial contributions on lactation and reproduction, growth, environmental aspects and maintenance. This book is essential reading for research workers in animal science, particularly those concerned with nutrition and feed evaluation.

      • Trusted Partner
        Zoology & animal sciences
        May 2021

        Nutrition and Feeding Organic Cattle

        by Robert Blair

        Organic cattle farming is on the increase, with consumer demand for organic milk and meat growing yearly. Beginning with an overview of the aims and principles behind organic cattle production, this book presents extensive information about how to feed cattle so that the milk and meat produced meet organic standards, and provides a comprehensive summary of ruminant digestive processes and nutrition. Since the publication of the first edition, global consumers have increasingly become concerned with the sustainability of meat production. Here, Robert Blair considers the interrelationships of sustainable practices and profitability of organic herds, reviewing how to improve forage production and quality, and minimizing the need for supplementary feeding using off-farm ingredients. This new edition also covers: - Managing a recurrent shortage of organic feed ingredients, due to increased GM feed crop cultivation worldwide - Current findings on appropriate breeds and grazing systems for forage-based organic production - Diet-related health issues in organic herds and the effects of organic production on meat and milk quality. Required reading for animal science researchers, advisory personnel that service the organic milk and beef industries and students interested in organic milk and meat production, this book is also a useful resource for organic farming associations, veterinarians, and feed and food industry personnel.

      • Trusted Partner
        Animal husbandry
        December 2005

        Quantitative Aspects of Ruminant Digestion and Metabolism

        by Edited by Jan Dijkstra, John M Forbes, James (Jim) France

        The first edition of this book, published in 1993, was very well received as providing a comprehensive review of the digestion and metabolism of ruminant animals. Since its publication, much new research has been conducted in the subject and knowledge has increased. This is incorporated in this second edition through the addition of five completely new chapters. These cover; the gas production technique in feed evaluation; calorimetry; the relationship between pasture characteristics and animal performance; feed processing; and the integration of data in feed evaluation systems. Other chapters have been fully expanded and updated as appropriate and Dr Dijkstra has also been enrolled as the lead editor. This book brings together quantitative approaches used in the study of mechanisms of ruminant digestion and metabolism.

      • Trusted Partner
        Medicine
        March 2017

        The metamorphosis of autism

        A history of child development in Britain

        by Keir Waddington, Bonnie Evans

        This book is available as an open access ebook under a CC-BY-NC-ND licence. What is autism and where has it come from? Increased diagnostic rates, the rise of the 'neurodiversity' movement, and growing autism journalism, have recently fuelled autism's fame and controversy. The metamorphosis of autism is the first book to explain our current fascination with autism by linking it to a longer history of childhood development. Drawing from a staggering array of primary sources, Bonnie Evans traces autism back to its origins in the early twentieth century and explains why the idea of autism has always been controversial and why it experienced a 'metamorphosis' in the 1960s and 1970s. Evans takes the reader on a journey of discovery from the ill-managed wards of 'mental deficiency' hospitals, to high-powered debates in the houses of parliament, and beyond. The book will appeal to a wide market of scholars and others interested in autism.

      • Trusted Partner
        History of medicine
        February 2017

        The metamorphosis of autism

        'A history of child development in Britain

        by Series edited by Professor Keir Waddington, Bonnie Evans

        What is autism and where has it come from? Increased diagnostic rates, the rise of the 'neurodiversity' movement, and growing autism journalism, have recently fuelled autism's fame and controversy. The metamorphosis of autism is the first book to explain our current fascination with autism by linking it to a longer history of childhood development. Drawing from a staggering array of primary sources, Bonnie Evans traces autism back to its origins in the early twentieth century and explains why the idea of autism has always been controversial and why it experienced a 'metamorphosis' in the 1960s and 1970s. Evans takes the reader on a journey of discovery from the ill-managed wards of 'mental deficiency' hospitals, to high-powered debates in the houses of parliament, and beyond. The book will appeal to a wide market of scholars and others interested in autism, neurodiversity and how this relates to wider theories of children's psychological development.

      • Trusted Partner
        Animal husbandry
        May 2000

        Farm Animal Metabolism and Nutrition

        by Edited by J P F D'Mello

        This book presents specially commissioned reviews of key topics in farm animal metabolism and nutrition, where major advances have recently been made or which continue to represent issues of significance for students and researchers.Advanced level textbook, no other advanced text in this area with such broad scopeFirst class contributors, including leading researchers from Europe, North America, South Africa and Australia

      • Trusted Partner
        Politics & government
        November 2006

        The European Union and the regulation of media markets

        None

        by Alison Harcourt

        National broadcasting and press regulation is undergoing a process of convergence in Europe. This book, newly available in paperback, explains how this process has been shaped by the actions of the European Union (EU) institutions. Alison Harcourt observes that whilst communications is one of the EU's most successful policy areas, European decision-making is eroding the national capacity to regulate for the public interest. European-level efforts to protect public interest goals have been constrained by the European Treaties. The author argues that increased European coordination in public interest regulation could be more conducive to growth and competitiveness than the dismantling of existing national laws. This, however, would require changes to the political composition of the European Union. This book assesses the potential EU media regulation provides for market growth and the protection of media pluralism, the citizen and ultimately democracy itself. These opportunities are presented in the coming decade with the developing European Constitution, EU enlargement, and the implementation and revision of European regulation.

      • Trusted Partner
        May 2022

        Mineral Nutrition Of Livestock 5th Edition

        by Neville Suttle

        The fifth edition of this important book reviews recent advances in livestock mineral nutrition, updated throughout with new references that reflect the growing complexity of mineral metabolism. Major related themes covered include the assessment of the 'mineral value' of feeds, the false hopes placed on organic mineral supplements and limiting the 'mineral footprint' of livestock production to lower environmental pollution. Also discussed are new developments and concepts including: Salt tolerance and optimizing production in salt-rich environments. Use of phytase rather than phosphate supplements in pig and poultry rations. Demineralization of the skeleton during confinement. Recognition of sub-acute, clinical hypocalcaemia as a disorder in dairy cows. The assay of 'free' plasma B12 to assess cobalt status of cattle. Limitations of cell culture and ligated loop techniques for assessing bioavailability. Following a clear and easy to reference structure, the book also considers potential pitfalls, such as misleading estimates of mineral requirements for growth, and misinterpretation of genomic markers for mineral requirements and bioavailability of supplements. An essential resource for researchers and students in animal nutrition, agriculture and veterinary medicine, this book also forms a useful reference for veterinary practitioners and those concerned with human nutrition and environmental protection.

      • Trusted Partner
        Humanities & Social Sciences
        March 2006

        EU pharmaceutical regulation

        The politics of policy-making

        by Govin Permanand, Dimitris Papadimitriou, Simon Bulmer, Andrew Geddes, Peter Humphreys, Caroline Wilding

        This book provides an analysis of European Union pharmaceutical regulation from a policy-making perspective. The focus is on how the often conflicting agendas of the pharmaceutical industry, the EU member states, the European Commission, and consumer interests are reconciled within the context of regulatory outcomes having to serve public health, healthcare and industrial policy needs within the single market. Breaking with more traditional approaches which stress the economic determinants of pharmaceutical policy, different strands of public policy analysis, regulatory and European integration and policy-making theories are invoked in developing a new conceptual approach to frame the analysis. In-depth case-studies in three key policy areas: patent protection, market authorisation, and pricing and reimbursement, provide substantive support. In providing a unique perspective on how and why EU pharmaceutical policy is made, the book will be of interest to academics, students and policy-practitioners interested in EU policy-making, regulation and public policy analysis. ;

      • Trusted Partner
        Microbiology (non-medical)
        January 1971

        Micro-organisms associated with oil palm

        by P D Turner

        Paper on micro-organisms associated with oil palm.

      • Trusted Partner
        January 2021

        The Endocrine System, Third Edition

        by Salvatore Blair, Ph.D. and Lynette Rushton

        Much like the nervous system, the endocrine system relays important communication signals throughout the body. The endocrine system uses chemical signals known as hormones, which are produced and stored in special glands in the body. Different glands produce specialized hormones and release them into the bloodstream. From there, these hormones can travel directly to the tissues and organs and help regulate bodily functions. In The Endocrine System, Third Edition, learn how this chemical messaging system is vital to the body’s growth, metabolism, and sexual development. Packed with full-color photographs and illustrations, this absorbing book provides students with sufficient background information through references, websites, and a bibliography.

      • Trusted Partner
        Geography & the Environment
        August 2022

        Key Questions in Environmental Toxicology

        A Study and Revision Guide

        by J P F D'Mello

        Key Questions in Environmental Toxicology is designed as a self-study tool for undergraduate students. Questions review the origin, characterization and environmental distribution of major pollutants, followed by their absorption and metabolic disposition in living organisms. They address implications for the development of cancer, cardiovascular disease, pulmonary dysfunction and neurological conditions in relation to gaseous pollutants, particulates, persistent organic compounds and radioactive emissions, then cover the impact of pollutants on biodiversity, food safety, and water contamination. This book: - Covers toxicology from human morbidity, ecological impact and biodiversity perspectives, and emphasises the impact of diverse organic pollutants in worsening these interconnected phenomena, leading to wider environmental emergencies; - Provides a selection of fill-in-the-gap, multiple choice and short answer question types for students to vary their learning and enhance motivation; - Includes full answer rationales, allowing students to gain true insight into the subject. Providing support to programmes across environmental science, ecology and human health, and covering all the major biological toxins and pollutants as well as unintended consequences of actions designed to improve outcomes, this book may be used in conjunction with the companion volume Introduction to Environmental Toxicology.

      • Trusted Partner
        Animal husbandry
        July 1999

        Regulation of Feed Intake

        by Edited by Daan van der Heide, E A Huisman, E Kanis, J W M Osse, M Verstegen

        Feed intake is the central issue in animal husbandry, being the key factor in determining health, welfare, environmental impact and productivity. With the focus on these issues, this book has been developed from the 5th Zodiac Symposium held in Wageningen in April 1998. The book reflects research conducted by observing natural behaviour, by investigating form-function relationships, physiology, metabolism and genetic make-up, and by offering choices of feed and environment. Information from studies on humans, wildlife and fish, as well as farm animals, is presented. It is divided into three parts:Natural Feeding, Feeding Modes, Preferences and BehaviourPhysiological Regulation of Feed Intake: Genetic, Metabolic, Hormonal and Neural RegulationsEnvironmental Factors and Feed Intake: Feeding Behaviour, Feed Choice and Feeding HabitsContributors include leading research workers from several European countries and Africa.

      • Trusted Partner
        Children's & YA
        January 2011

        The Boy Who Saw the Color of Air

        by Abdo Wazen

        In his first YA novel, cultural journalist and author Abdo Wazen writes about a blind teenager in Lebanon who finds strength and friendship among an unlikely group.   Growing up in a small Lebanese village, Bassim’s blindness limits his engagement with the materials taught in his schools. Despite his family’s love and support, his opportunities seem limited.   So at thirteen years old, Bassim leaves his village to join the Institute for the Blind in a Beirut suburb. There, he comes alive. He learns Braille and discovers talents he didn’t know he had. Bassim is empowered by his newfound abilities to read and write.   Thanks to his newly developed self-confidence, Bassim decides to take a risk and submit a short story to a competition sponsored by the Ministry of Education. After winning the competition, he is hired to work at the Institute for the Blind.   At the Institute, Bassim, a Sunni Muslim, forms a strong friendship with George, a Christian. Cooperation and collective support are central to the success of each student at the Institute, a principle that overcomes religious differences. In the book, the Institute comes to symbolize the positive changes that tolerance can bring to the country and society at large.   The Boy Who Saw the Color of Air is also a book about Lebanon and its treatment of people with disabilities. It offers insight into the vital role of strong family support in individual success, the internal functioning of institutions like the Institute, as well as the unique religious and cultural environment of Beirut.   Wazen’s lucid language and the linear structure he employs result in a coherent and easy-to-read narrative. The Boy Who Saw the Color of Air is an important contribution to a literature in which people with disabilities are underrepresented. In addition to offering a story of empowerment and friendship, this book also aims to educate readers about people with disabilities and shed light on the indispensable roles played by institutions like the Institute.

      • Trusted Partner
        Fiction
        May 2020

        The Guys of Rangoon 1930

        by Khet Zaw

        The Guys of Rangoon , 1930 is a record breaking bestseller book from Myanmar . It sold 16000 copies within one day during the pre order period. More than one hundred thousand copies have been sold so far. Film rights, several merchandise rights, comic rights already sold.It was based in Yangon , Myanmar during the colonial period. The main character is Pho Thoke who was a gangster and managed a lot of business by himself and his gang. He is very close with politicians as well and he is involved in several dirty political movements in Myanmar . This story is based on real characters and events.

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      • Trusted Partner
        Business, Economics & Law
        May 2024

        Governance, democracy and ethics in crisis-decision-making

        The pandemic and beyond

        by Caroline Redhead, Melanie Smallman

        This book is a powerful addition to a developing literature informed by arts and humanities research carried out during the COVID-19 pandemic. Investigating the impacts of crisis governance and decision-making on people and populations, the book brings together microbial organisms and humans, children and data, decision-making and infection prevention, publics and process, global vaccine distribution and citizens' juries. Through its eight chapters, the book stimulates broadly-drawn discussions about exceptional executive powers in an emergency, the role of trust, and the importance of the principles of good governance - such as selflessness, ethics, integrity, accountability and honesty in leadership. The lessons drawn out in this book will support future decision-makers in both ordinary times and extra-ordinary emergencies.

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