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      • Naufal Hachette Antoine

        In 2009, Hachette Livre (# 3 publishing group worldwide) and Librairie Antoine (one of the most renowned Lebanese bookseller groups) joined their strengths to set up Hachette Antoine, a joint-venture based in Beirut, Lebanon. The aim of the JV between Hachette Livre and Librairie Antoine was to create a leading trade publisher in the Arabic speaking world, covering the Middle East (Levant and GCC) and North-Africa regions, with a business focus on high potential markets. Our strength: • Large-scale distribution channels in the MENA region with warehouses in Lebanon, Saudi Arabia, UAE and Egypt. • Strong PR and Media connections throughout the region with efficient online and offline marketing tools. • The only Arab publishing house to provide professional and exhaustive editing on both translated and original Arabic books. • Full financial transparency: All audit assertions and financial statements are served by PricewaterhouseCoopers. Our imprints Naufal: is dedicated to fiction and non-fiction. Our list includes well established classical and contemporary authors from the Arab world among which the best-selling/phenomenon Algerian author, Ahlem Mosteghanemi, Syrian novelist Khaled Khalifa, and Lebanese journalist and women’s rights activist, Joumana Haddad. Fiction/translated: In translated fiction, our strategy consists of publishing authors from Arab origins who write in languages other than Arabic, alongside international best-selling authors. We also leave room for a few “coups de cœur” by debut authors. Thrillers and suspense: Include names such as J.K. Rowling aka Robert Galbraith, Mary Higgins Clark, Harlan Coben, Anthony Horowitz and others, and providing quality translations. Non-Fiction: Biographies and Memoirs: Becoming, A promised land. HA Kids: Licenses: Hachette Antoine is the official licensee of Disney, Marvel, Star Wars, Nickelodeon, Ferrari... in the MENA region, with more brands to come. History and Topical books, Illustrated, Inspirational stories, HA Lifestyle, HA Education, HA Reference

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      • Trusted Partner
        Lifestyle, Sport & Leisure
        September 2023

        Pre and Probiotics for Poultry Gut Health

        by Helen Masey O'Neill, Emily Burton, Dawn Scholey

        Poultry are the most widely used animal protein source in the world: billions of meat birds are produced globally each year, using 360 million tonnes of feed. Within Europe, over 30,000 companies involved in the production of poultry create an annual turnover of €107 billion. However, maintaining the sustainability of the industry as it moves towards antibiotic-free production is one of the key challenges. Starting with an overview of antibiotics as growth promoters and the challenges faced as the industry moves away from their use, this book then thoroughly considers the potential of pre and probiotic additives in poultry gut health. The book: - Includes thorough definitions of additives in the pre and probiotic space and examples of how they work; - Addresses how to test pre and probiotics and other similar additives, and how they interact with other products, with learning from both poultry and allied sectors; - Combines authors from both academic and industry backgrounds on all chapters, to ensure coverage is balanced, robust and commercially relevant. Based on the renowned World Poultry Science Association UK Branch Poultry Science Symposium 2022, this book provides a thorough and valuable contribution to the field for all involved with the nutrition and production of poultry.

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        2020

        Lighthouses

        Successful Pharmacologists in the 20th Century

        by Ernst Mutschler, Christoph Friedrich

        Antibiotics, insulin, cortisone: countless medicines, which are now lifesavers, were still undiscovered in 1900. Since then, there have been impressive advances in pharmaceutical research. This book is dedicated to all those whom we have to thank for this. While today research is conducted by university teams and working groups in industry, during the early decades of the 20th century it was primarily individual researchers whose ingenuity led to the development of new agents. An introduction to these ‘lighthouses’ in the fields of chemistry, biology, pharmacy and medicine, and to their successes.

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        2023

        The big PTAheute Handbook

        Practical knowledge for the pharmacy

        by Edited by Dr. Iris Milek

        Already in its 3rd edition, the PTAheute handbook presents the essence of practical pharmacy knowledge and is becoming the standard work for a practical pharmacy. PTAheute authors contribute their professional experience and bundle the most important facts, in the proven manner of the trade journal PTAheute: ■ Comprehensibly prepared content facilitates putting knowledge effectively into practice. ■ Infographics help readers understand the contexts. ■ Yellow boxes provide a quick overview. ■ Pictures and graphic design increase reading pleasure. The content on multiple sclerosis or on the various aspects of Covid-19 is new to the 3rd edition. The chapters on „Antibiotics“ and „Interactions“ have been completely restructured and revised and all other content has been brought fully up to date. The PTAheute handbook – the reliable companion in everyday pharmacy life!

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        Human biology
        February 2020

        Antimicrobial Stewardship for Nursing Practice

        by Molly Courtenay, Enrique Castro-Sánchez, Bri?tte du Toit, Yolanda van Zyl, Maria Clara Padoveze, Ligia Maria Abraão, Rosely Moralez de Figueiredo, Jo McEwen, Heather Kennedy, Nykoma Hamilton, Emma Burnett, Valerie Ness, Fiona Gotterson, Elizabeth Manias, Rose Gallagher, Rita Olans, Susie Singleton, Joanne Bosanquet

        Multi-drug resistant infections are one of the greatest threats to human health, and with resistance on the rise, appropriate antimicrobial stewardship (AMS) is more important than ever. This book, written by nurses for nurses, provides a clear and concise approach to good practice in this vital area. It explores all aspects of AMS, explaining the practices that ensure the optimal use of antibiotics for the best clinical outcome, with both minimal toxicity to the patient and minimal impact on subsequent antimicrobial resistance. Written by a global team of experts, it covers infection prevention and control, antimicrobial resistance, diagnosis of infection and appropriate antimicrobial use, patient engagement, collaboration between professions and how to implement AMS in nursing practice. The first AMS textbook applied directly to nursing practice, and underpinned by a competency framework designed by the editor team, it includes learning tools such as objectives, practical case studies and questions throughout.

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        Zoology & animal sciences
        May 2021

        Nutrition and Feeding Organic Cattle

        by Robert Blair

        Organic cattle farming is on the increase, with consumer demand for organic milk and meat growing yearly. Beginning with an overview of the aims and principles behind organic cattle production, this book presents extensive information about how to feed cattle so that the milk and meat produced meet organic standards, and provides a comprehensive summary of ruminant digestive processes and nutrition. Since the publication of the first edition, global consumers have increasingly become concerned with the sustainability of meat production. Here, Robert Blair considers the interrelationships of sustainable practices and profitability of organic herds, reviewing how to improve forage production and quality, and minimizing the need for supplementary feeding using off-farm ingredients. This new edition also covers: - Managing a recurrent shortage of organic feed ingredients, due to increased GM feed crop cultivation worldwide - Current findings on appropriate breeds and grazing systems for forage-based organic production - Diet-related health issues in organic herds and the effects of organic production on meat and milk quality. Required reading for animal science researchers, advisory personnel that service the organic milk and beef industries and students interested in organic milk and meat production, this book is also a useful resource for organic farming associations, veterinarians, and feed and food industry personnel.

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        Medicine
        December 2016

        Antimicrobial Stewardship

        Principles and Practice

        by Kerry LaPlante, Cheston Cunha, Haley Morrill, Louis Rice, Eletherios Mylonakis

        In an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection. This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection. Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration. ; Antimicrobial research has hit a wall: treatment discoveries are rarer and resistant pathogen strains more prevalent. Rather than infection control itself, antimicrobial stewardship is an essential measure in ensuring management of hospital-acquired infections. Throughout this book, international experts discuss all angles of stewardship. ; Part I: Overview of Antibiotic StewardshipCh.1: Principles of Antimicrobial StewardshipCh 2: Clinical Perspective of Antimicrobial StewardshipCh 3: History of Antimicrobial StewardshipCh 4: The Importance of Education in Antimicrobial StewardshipPart II: Antibiotic Resistance Principles in Antibiotic Stewardship Ch 5: Intrinsic and Acquired Mechanisms of ResistanceCh 6: Antimicrobial Resistance: Selection vs. InductionCh 7: Colonization and its importance for emergence of clinical resistanceCh 8: Antibiotic Resistance: associations and implications for antibiotic usage strategies to control multi-resistant bacteriaPart III: Microbiology Laboratory Role in Antibiotic StewardshipCh 9: The role of active surveillance in the prevention of healthcare-acquired infections and antibiotic stewardshipCh 10: Role of Antibiogram in Antibiotic StewardshipCh 11: Selective Reporting and Antimicrobial StewardshipCh 12: Role of New Diagnostics to Enhance Antibiotic Stewardship EffortsPart IV: Infection Control Aspects of Antibiotic StewardshipCh 13: Epidemiology of S aureus and enterococci in children and an overview of antimicrobial resistanceCh 14: Epidemiology of multi-drug resistant gram-negative organismsCh 15: Pathogenesis and Epidemiology of Clostridium difficile Infection: Implications for Antibiotic StewardshipCh 16: Role of the Hospital Epidemiologist in Supporting Antimicrobial StewardshipPart V: Pharmacokinetic (PK) & Pharmacodynamic (PD) Aspects of Antibiotic Dosing in Antibiotic StewardshipCh 17: Principles of Pharmacokinetic / Pharmacodynamic Optimization for Antibiotic DosingCh 18: Optimal use of Gram-negative antibiotics in the real world: providing effective therapy while minimizing resistanceCh19: Optimal Use of FluoroquinolonesCh 20: Optimal Use of Beta-lactam AntibioticsCh 21: Current Approach to Optimal Use and Dosing of Vancomycin in Adult PatientsCh 22: Principles of IV to PO SwitchPart VI: Pharmacy Department Role in Antibiotic StewardshipCh 23: Role of Pharmacists in Antimicrobial StewardshipCh 24: Formulary Management and Economic Considerations; Bridging the Gap between Quality Care and CostCh 25: Approaches in benchmarkingCh 26: Development and execution of stewardship interventionsCh 27: Technologic support for antimicrobial stewardshipPart VII: Measuring Outcomes in Antibiotic Stewardship ProgramsCh 28: Role of Guidelines and Statistical Milestones for Antimicrobial StewardshipCh 29: Economic considerations of Antimicrobial Stewardship ProgramsCh 30: Pharmacoeconomic Implications of Antimicrobial Adverse EventsCh 31: Antimicrobial stewardship programs in areas of increased pathogen resistancePart VIII: Antimicrobial Stewardship and Various Practice SitesCh 32: Role of Antimicrobial Stewardship in PediatricsCh 33: Antimicrobial Stewardship in the Intensive Care UnitCh 34: Role of Antimicrobial Stewardship in a Community HospitalCh 35: Outpatient Parenteral Antimicrobial Therapy (OPAT)Ch 36: The Importance of Interdisciplinary Collaboration in Antimicrobial Stewardship: Immersion of Future Healthcare ProfessionalsCh 37: Antimicrobial Stewardship and the Importance of Working with the Government and Pharmaceutical IndustryCh 38: Hospitalist Perspective on the Role of Antimicrobial Stewardship

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        January 2020

        Typhoid Fever, Second Edition

        by Donald Emmeluth, Ed.D.

        Typhoid fever is caused by the bacterium Salmonella typhi, and it is usually spread through feces-contaminated food and water. Although it still occurs frequently in underdeveloped countries, typhoid fever is virtually unknown in the industrialized world. Common symptoms of the disease include fever, headaches, nausea, and vomiting. Though treatable with antibiotics, antibiotic resistance is a serious concern and the subject of continuing research efforts. Typhoid Fever, Second Edition discusses the history of the disease, the microbiology of the typhoid bacterium, signs and symptoms of the disease, treatment and prevention options, concerns for the future, and topics and applications of current research. Chapters and topics include: History of Typhoid Fever Salmonella Typhi Diagnosing Typhoid Fever Treating Typhoid Fever Preventing Typhoid Fever Antibiotic Resistance and Treating Typhoid Fever Typhoid Fever and Future Concerns Typhoid Fever and Hopes for the Future.

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        January 2020

        Staphylococcus aureus infections, Second Edition

        by Donald Emmeluth, Ed.D.

        Staphylococcus aureus is a common bacterium found on the skin and in the nose of up to 25 percent of healthy people and animals, according to the Centers for Disease Control and Prevention. S. aureus causes a wide variety of infections, most of which are localized to the skin and are nonfatal in nature. The bacterium produces superficial skin lesions, but can also cause serious internal infections, including hospital-acquired pneumonia, meningitis, septic arthritis, osteomyelitis, endocarditis, and bacteremia. Some strains of S. aureus are resistant to antibiotics, including methicillin-resistant Staphylococcus aureus (MRSA), making treatment challenging. Staphylococcus aureus Infections, Second Edition describes the symptoms, diagnosis, treatment, and prevention of S. aureus infections, the newest related research, and future prospects for controlling the bacteria. Chapters and topics include: Bacteria Staphylococcus aureus Staphylococcus aureus, the Immune System,and Bacterial Virulence Factors Fighting Staphylococcus aureus Infections Staphylococcus aureus and Mechanisms of Resistance Methicillin- and Vancoymcin-Resistant Staphylococcus aureus Staphylococcus aureus and Prevention of Antibiotic Resistance The Future of Staphylococcus aureus Treatment.

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        Veterinary medicine
        December 2006

        Avian Gut Function in Health and Disease

        by Edited by Graham C. Perry

        Derived from the 28th Poultry Science Symposium of the World's Poultry Science Association (UK), this book focuses on the current interest of the phasing out of antibiotic use in poultry and covers in-depth interactions between the bird, its diet and potential pathogens. It also demonstrates the understanding of the gut health in the 21st century of commercial poultry and flocks and the ultimate safety of poultry product in the human food chain.

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        Medical microbiology & virology
        November 2010

        Antimicrobial Peptides

        Discovery, Design and Novel Therapeutic Strategies

        by Edited by Guangshun Wang.

        Antimicrobial Peptides (AMPs) are an organism's built-in defence molecules that have attracted extensive research attention worldwide. Harnessing and creating them synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. In addition to covering the current advances in AMP research, this volume examines new technologies such as bioinformatics, combinatorial libraries, high-throughput screening, peptidomimetics, biophysics, and structural biology. This volume also describes new methods and strategies for AMP prediction, design, and applications that overcome obstacles in developing them into therapeutic agents.

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        Medical microbiology & virology
        June 2010

        Helicobacter pylori in the 21st Century

        by Steffen Backert, Stefan Bereswill, Tom Blanchard, Pelayo Correa, Richard Ferrero, Kwong-Ming Fock, Sara Lindén, Hoda Malaty, Barry Marshall, Francis Megraud, Anthony P Moran, John Nedrud, Karen Robinson, Maria Kaparakis. Edited by Philip Sutton, Hazel Mitchell.

        Helicobacter pylori is a globally significant pathogen that infects half of the population of the world. Its recognition enabled the development of new therapeutic and preventative strategies for serious health conditions such as gastric cancer, of which it is the major causative agent. Providing a broad overview of the current understanding of this pathogen and emphasising its world health impacts, this book explores a range of topics including virulence factors, vaccine development and obstacles, epidemiology, antibiotic resistance and the role of Nod receptors, with a foreword by Barry Marshall, the Nobel Laureate and co-discoverer of H. pylori. It is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

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        January 2019

        Gonorrhea, Third Edition

        by Brian R. Shmaefsky, Ph.D.

        Gonorrhea is a common sexually transmitted disease. More than 700,000 people are infected annually in the United States, according to the Centers for Disease Control and Prevention. It is curable with antibiotic treatment, and its dangerous effects can be prevented if it is identified and treated early in its development. Gonorrhea, Third Edition looks at the disease from historical and epidemiological perspectives, describing the discovery of the bacterium that causes gonorrhea, how it can be prevented, and the development of effective treatments.  Chapters include: What Is Gonorrhea? History of Gonorrhea and Sexually Transmitted Diseases Symptoms and Diagnosis of Gonorrhea Epidemiology of Gonorrhea Complications and Treatment of Gonorrhea The Future of Gonorrhea.

      • Trusted Partner
        Medicine
        September 2017

        Antimicrobial Peptides

        Discovery, Design and Novel Therapeutic Strategies

        by Guangshun Wang

        Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide. Harnessing and creating AMPs synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. This new edition lays the foundations for studying AMPs, including a discovery timeline, terminology, nomenclature and classifications. It covers current advances in AMP research and examines state-of-the-art technologies such as bioinformatics, combinatorial libraries, high-throughput screening, database-guided identification, genomics and proteomics-based prediction, and structure-based design of AMPs. Thoroughly updated and revised, this second edition contains new content covering: defensins; cathelicidins; anti-MRSA, antifungal, antiviral, anticancer and antibiofilm strategies; combined treatments; adjuvants in vaccines; advances in AMP technologies that cover surface coating to prevent biofilm formation; nanofiber encapsulation technologies for delivery and sustained release; and understanding innate immunity and the basis for immune boosting to overcome obstacles in developing AMPs into therapeutic agents. Written and reviewed by a group of established investigators in the field, Antimicrobial Peptides is a valuable resource for postgraduate students, researchers, educators, and medical and industrial personnel.

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        December 2021

        Enzymes in Farm Animal Nutrition

        by Michael R Bedford, Gary G Partridge, Carrie Walk, Milan Hruby, Ceinwen Evans, Hamish Irving, Jari Vehmanperä, Kari Juntunen, John Patience, Qingyun Li, Amy Petry, Jason Lee, Kyle Brown, Aaron Cowieson, Daniel Menezes-Blackburn, Ralf Greiner, Ursula Konietzny

        From alpha-galactosidases to xylanases, Enzymes in Farm Animal Nutrition provides a comprehensive guide to all aspects associated with enzyme-supplemented animal feeds. It details the history and size of the feed enzyme market, before describing how feed enzymes are manufactured and employed in monogastric, aqua and ruminant diets. This new edition explores considerable advances such as the use of enzymes in fish and shrimp diets, new understanding of how phytases function in the animal, NSPase research and enzymes' extended use in ruminant markets. It also: - Provides comprehensive coverage of all topics relating to the production, use, and co-operativity and analysis of feed enzymes; - Is fully updated throughout, revealing significant developments such as new methods to deliver enzymes (formulations, encapsulations, and liquid spray systems) and advances in enzyme analysis; - Includes brand new chapters on combinations of enzymes, antibiotic free diets and how to measure response in feed enzyme trials. Covering biochemistry, enzymology and characteristics relevant to animal feed use, this book forms a valuable resource for academics and students of animal nutrition and production, as well as professionals in the animal feed industry.

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        January 2022

        Plague, Third Edition

        by Donald Emmeluth, Ed.D.

        Plague has erupted periodically throughout most of human history. The plague bacterium, Yersinia pestis, is transmitted by fleas found on many common mammals and through the air as victims develop respiratory symptoms and suffer from coughing spells. This easy transmission has made plague responsible for some of the highest death rates from any epidemic disease in history. Plague, Third Edition examines the disease from an epidemiological perspective. Studies of the historical European plague outbreaks, known as the Black Death, examine the role animals play in the spread of disease and the human cost of such a widespread outbreak. This revised edition includes new photographs and illustrations as well as updated statistics on modern plague outbreaks in the American southwest.  Chapters include: Historical Overview Causes of the Plague Animal Plague Vectors Diagnosis Treatment Prevention The Problems of Antibiotic Resistance Concerns for the Future Hopes for the Future.

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        January 2020

        Streptococcus (Group A), Third Edition

        by Brian R. Shmaefsky, Ph.D. and Tara C. Smith, Ph.D.

        Group A streptococci (Streptococcus pyogenes) are probably best known for causing streptococcal pharyngitis, or strep throat. But they also cause more kinds of disease than any other species of bacteria. Group A streptococci are responsible for diseases that range from mild skin conditions to scarlet fever to rheumatic fever to the devastating and sometimes deadly necrotizing fasciitis, commonly known as "flesh-eating bacteria." This revision of Streptococcus (Group A) examines the history, epidemiology, and future prospects for the ongoing battle against group A streptococci, and provides up-to-date information on research breakthroughs and the latest outbreaks of group A diseases. Updates include information on antibiotic resistance, current research on scarlet fever, and the progress on a vaccine. Chapters include: One Bacterium, Many Different Diseases Diagnosis and Treatment of the Group A Streptococcus Superficial Infections: Streptococcal Pharyngitis and Impetigo Scarlet Fever Resurgence of an Old Pathogen: Invasive Streptococcal Diseases Post-Streptococcal Complications Virulence Factors of Group A Streptococci Vaccine Prospects and the Future of the Group A Streptococcus.

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        Medical microbiology & virology
        May 2014

        Human Microbiota and Microbiome

        by Markus Egert, Wim Crielaard, Larry Forney, Ken Bruce, Huiying Li, Takahiro Matsuki, Tom van de Wiele, Andrew Goodman, Marco Ventura, Jia Li, Elaine Holmes. Edited by Julian R Marchesi.

        Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.

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