• Medicine
      September 2014

      The Dark Side, Real Life Accounts of an NHS Paramedic

      The Good, the Bad and the Downright Ugly

      by Andy Thompson

      Andy Thompson’s true-to-life, graphic and gripping account of his work as an NHS paramedic in Britain’s A&E emergency Ambulance Service will shock you, sadden you, entertain you, and perhaps inspire you. You’ll smile at some of Andy’s real patient encounters, while others will cause you to wipe a tear. Using official NHS documentation recorded at the time to give precise details of each incident, Andy has held firm to the real-life accounts, even in keeping the dialogue as close as his memory allows to what was really said at the time. It’s as if you’re there next to him, struggling with the effects of adrenaline and fighting to save life. This is a rare work of medical non-fiction delivered in a way that is factual, informative, but at the same time naturally entertaining and moving, written with candour and humour. And if you have ever thought what it takes to become a paramedic - or any other of the specialist vocations - and that you could never achieve it yourself, Andy’s inspiring story of how he went from postman to frontline healthcare professional, fulfilling his dream, will make you think again that anything is possible if you have the desire. Andy says there are no heroics in the book and that he simply did his job, but we are sure The Dark Side will leave you convinced there are true heroes on our streets right here, right now. Saving lives every day, every night and often against all the odds. It might even change your whole perspective on life.

    • Chiropody & podiatry

      A Guide to Research for Podiatrists

      by Jackie. Campbell

      It is constantly suggested that, as podiatrists, we need to research, but what does this really mean? This question can be particularly problematic in a profession such as podiatry, where there has not been a strong research basis for our practice in the past. Information is no longer accepted at face value, but instead is scrutinised, criticised, questioned and used to raise other questions. Podiatrists are being prepared to understand, use and undertake their own research. The book will appeal to podiatry practitioners, lecturers and students. It is based on a popular series of articles that appeared in Podiatry Now, which have been updated and edited into this stand-alone resource.

    • Fiction
      November 2011

      Code Blood

      by Kurt Kamm

      Colt Lewis, a rookie fire paramedic, is obsessed with finding the severed foot of his first victim after she dies in his arms. His search takes him into the connected lives of a graduate research student, with the rarest blood in the world and the vampire fetishist who is stalking her. Within the corridors of high-stakes medical research laboratories, the shadow world of body parts dealers, and the underground Goth clubs of Los Angeles, Lewis uncovers a tangled maze of needles, drugs and maniacal ritual, all of which lead to death. But whose death? An unusual and fast-paced LA Noir thriller.

    • Adventure

      Erupting Lies

      by Beverley Bassett Broad

      3rd Book in a historical Saga Covers the eruption of Mount Tarawera in New Zealand and exciting dramatic events between NZ and Europe

    • Teaching, Language & Reference
      October 2018

      Mikromechanische Antriebstechnik

      für aktive Augenimplantate

      by Thomas Martin

      Das Buch beschreibt erstmals die Entwicklung von mechanischen Antrieben für die aktive Optik des Künstlichen Akkommodationssystems. Das intraokulare, mechatronische Implantat soll die Akkommodationsfähigkeit des menschlichen Auges bei Alterssichtigkeit oder im Rahmen einer Kataraktoperation wiederherstellen. Dafür besonders geeignete optische Wirkprinzipien sind nach früheren Forschungsergebnissen Linsensysteme mit parallel oder senkrecht zur optischen Achse zu verschiebenden Linsenkörpern in Form einer Triple-Optik und einer Alvarez-Optik. Beide benötigen einen mechanischen Antrieb. Eine Analyse der notwendigen Funktionen des Antriebs bildet die Grundlage für die Entwicklung der Funktionsstruktur eines generischen Lösungskonzepts. Für alle Teilfunktionen werden Lösungsansätze in Form von Wirkprinzipien erarbeitet. Mit ihnen wird das generische Antriebskonzept schließlich als Wirkstruktur formuliert Auf Basis dieses Konzepts werden Antriebsentwürfe für eine Triple-Optik und eine Alvarez-Optik funktions-, fertigungs- und montagegerecht ausgearbeitet. Sie basieren auf piezoelektrischen Aktoren zur mechanischen Bewegungserzeugung. Für beide Antriebe werden planare Getriebe aus einkristallinem Silizium mit jeweils einem neuartigen elastischen Verformungsmechanismus entwickelt. Neben theoretischen Funktionsnachweisen wurden beide Antriebslösungen als Funktionsmuster im Maßstab 1,5:1 bzw. 1,2:1 entworfen, aufgebaut, erfolgreich in Betrieb genommen und mit positivem Ergebnis messtechnisch charakterisiert. Damit wird erstmals die Realisierbarkeit mechanischer Antriebe für das Künstliche Akkommodationssystem nachgewiesen.

    • Teaching, Language & Reference
      April 2018

      Gewinnung von Bilddaten

      Automatisierung in der Diagnostik am Beispiel der Kornea

      by Stephan Allgeier

      Das Buch beschreibt eine dedizierte Prozesskette zur Gewinnung der anschließenden Fusion von Bilddaten. Beide Prozesse stellen in wesentlichen Teilen Neuentwicklungen dar und werden ausführlich hergeleitet und beschrieben. Das vorgestellte Konzept ermöglicht eine automatische großflächige Bildgebung, die insbesondere in der medizinischen Diagnostik Anwendung findet. Hier wird es beispielhaft vom Nervenplexus in der zentralen Kornea abgeleitet.

    • Medicine
      April 1985

      Aspartic Proteinases and Their Inhibitors

      Proceedings of the FEBS Advanced Course No. 84/07, Prague, Czechoslovakia, August 20–24, 1984

      by Vladimír Kostka, Federation of European Biochemical Societies

    • Medicine
      June 2018

      Biosignalverarbeitung

      Grundlagen und Anwendungen mit MATLAB

      by Stefan Bernhard, Andreas Brensing, Karl-Heinz Witte

      Das interdisziplinäre Feld der Biosignalverarbeitung ist aus heutigen Anwendungen der Medizintechnik nicht mehr wegzudenken. Dieses Grundlagenbuch liefert nicht nur eine allgemeine Einführung zur Entstehung, Messung und analogen wie digitalen Weiterverarbeitung von Biosignalen. Es diskutiert auch weiterführende Themen in Form von modernen Anwendungsbeispielen. Es dient Lehrenden Lernenden als Einstieg in die Methodik, aber auch als Nachschlagewerk für Anwender in der Medizintechnik- und Informatik. Wegen der zahlreichen aktuellen Forschungsthemen wird es sogar Forschern der Natur- und Lebenswissenschaften vielfältige Impulse zur Entwicklung neuer Methoden zur Verarbeitung von Biosignalen geben. Aus dem Inhalt Entstehung von Biosignalen, Elektrophysiologie, analoge und digitale Biosignalverarbeitung, Diskretisierung, Störungseinkopplung, Ableitungselektroden, Analyse im Zeit- und Frequenzbereich, analoge und Digitale Filter, Faltung, diskrete Fouriertransformation, z-Transformation, Merkmalsbestimmung, Merkmalsauswahl, Mustererkennung, Klassifikation, statistische Datenauswertung, Korrelation, Ereigniskorrelation, kohärente Mittelungsverfahren, PCA, ICA, physiologische Modellbildung, Anwendungen und Beispiele an EEG, EKG, EMG und PPG Daten.

    • Medicine
      April 2018

      Praktische Labordiagnostik

      Lehrbuch zur Laboratoriumsmedizin, klinischen Chemie und Hämatologie

      by Harald Renz

      Die 3., aktualisierte Auflage des Lehrbuches bereitet Medizinstudenten und Ärzte in der Weiterbildung optimal auf das Prüfungsfach Laboratoriumsdiagnostik/Klinische Chemie vor. Nicht nur Grundwissen wird vermittelt, sondern vor allem die praktische Anwendung einer rationalen und rationellen Labordiagnostik in den Organfächern und der Pädiatrie. Im ersten Teil werden die wichtigsten Organ- u. Stoffwechselsysteme (wie Kohlenhydratstoffwechsel, Niere und ableitende Organsysteme, Immunsystem) hinsichtlich ihrer labordiagnostischen Parameter einheitlich dargestellt, wobei ausgewählte Laborparameter und Erkrankungen am Kapitelanfang aufgeführt sind. Zudem werden Praxisbeispiele einer gezielten Stufendiagnostik bei Vorliegen eines bestimmten Krankheitsverdachts anhand von sogenannten »Entscheidungsbäumen« demonstriert und erläutert. Der zweite Teil gibt einen prüfungsrelevanten Überblick über die allgemeine und spezielle klinisch-chemische Analytik sowie die Präanalytik. Die dritte Auflage hat es sich zum Ziel gesetzt, noch mehr die praktische Anwendung der Laboratoriumsdiagnostik in den Mittelpunkt zu stellen. So kommt der kombinatorischen Betrachtung mehrerer Laborparameter in der Diagnose- und Verlaufsbeurteilung von Erkrankungen eine noch größere Bedeutung zu. Biomarker werden entwickelt, um Patienten im Rahmen »individualisierter« Therapiestrategien noch gezielter auszuwählen. Dieses Konzept, das ursprünglich aus der Tumortherapie entwickelt wurde, findet nunmehr auch breite Anwendung in anderen Krankheitsfeldern. Damit nimmt auch die Bedeutung von diagnostischen Algorithmen zu. Weitere Kapitel wurden ergänzt, wie das Neonatalscreening und das therapeutische Drug Monitoring. Zahlreiche farbige Abbildungen, Tabellen, Merksätze und Zusammenfassungen sowie Übungsfragen lockern den Textinhalt auf und veranschaulichen den Lernstoff.

    • Human-computer interaction
      June 2011

      Simulation-based Medical Training

      A User-Centred Design Perspective

      by Author(s): Erik Lövquist

      This volume explores the development process of a Virtual Reality (VR) and web-based medical training system from a user-centred perspective. It highlights the importance of user participation in this context by analysing two case studies concerned with the development of a VR and web-based medical training system for Spinal Anaesthesia.It illustrates the relationship between user participation and the development process of a VR and web-based medical training system. User groups, along with their input and degrees of participation and influence, are classified. It shows how a democratic arrangement between users and developers is beneficial and maybe even mandatory in order to utilise the users’ guidance efficiently. In this arrangement, the use of prototypes is instrumental in bridging the expertise and knowledge gap between users and developers.Reading this volume may aid other research teams developing VR and web-based medical training systems in deciding if, why and how to involve relevant user groups in the overall development process.

    • Biology, life sciences
      October 2014

      Medical and Applied Malacology Crossing Boundaries

      Integrative Approaches to Malacology

      by Editor(s): Ana Rita de Toledo Piza, Lenita de Freitas Tallarico, Gisele Orlandi Introíni and Sonia Barbosa dos Santos

      This book provides an overview of the XI International Congress on Medical and Applied Malacology: “Crossing Boundaries: Integrative Approaches to Malacology”. The event was held at the State University of Rio de Janeiro between the 25th and 29th of September 2012.A number of the plenary lecturers from the conference were invited to contribute their papers to these proceedings, as were speakers whose papers were eligible for student awards. The volume contains articles on bioprospecting methods; medical malacology; aquaculture; biomonitoring; alien species; reproductive and developmental biology; interdisciplinary teaching and education; and trends in malacological research.The information contained here will convey to the general public the importance of mollusks to human and animal health, as well as their applications in various areas of knowledge.

    • Physiology
      September 2013

      Vascular Function and Structure in the Rat Aorta

      by Author(s): Keith Wan Kee Ng

      One of the inevitable consequences of ageing is the progressive widening of pulse pressure resulting from stiffening of large arteries. While a large body of literature has been devoted to understanding blood pressure, a parameter proven to be predictive of cardiovascular health, very few books are devoted to explaining arterial stiffening, how it worsens, and why is it important for physicians to consider arterial stiffening when treating resistant hypertension. This book fills this gap. The fundamental purpose of this book is to systematically explain the pathophysiology behind arterial stiffness, to relate arterial stiffness with high blood pressure, and also to draw insights into the management of arterial stiffness from the current clinical and experimental research evidence in the field.Set out systematically, the book provides a readable and concise introduction to arterial stiffness and progressively moves into explaining more complex theoretical and experimental developments in the area. The book is designed such that each chapter largely answers a particular scientific question – covering the most up-to-date research information, investigations, and summaries and conclusions relating to the initial question. Future directions and research opportunities in the field are also covered.The book covers the most recent in vivo assessments of aortic stiffness in different phenotypes by measuring local haemodynamic parameters, pulse wave velocity, and pulse pressure amplification. Furthermore, the book relates ex vivo arterial structural properties and explains how they are relevant to arterial stiffness measurement, while also analysing recent pharmacological treatments of hypertension and assessing if these treatments have any effect on arterial stiffness in addition to treating blood pressure alone. Finally, the text offers a summary and appraisal of the methodologies used in experimental quantification of arterial stiffness.

    • Medical research
      January 2015

      Community, Autonomy and Informed Consent

      Revisiting the Philosophical Foundation for Informed Consent in International Research

      by Author(s): Pamela J. Lomelino

      In using the example of informed consent guidelines for international research on human subjects, this book demonstrates one of the many useful ways that philosophy can be used to move from theory to praxis by providing a general picture of how a philosophical analysis of underlying concepts can affect the way that public policy is framed; the ways that such policies are exclusionary; and a general methodology for remedying injustices in public policy and practice once they have been identified.With diseases, such as AIDS, reaching epidemic proportions in less developed countries, medical research on human subjects in these areas is on the rise. Current international guidelines for research on human subjects stress the importance of informed consent, which is meant to ensure that people freely choose whether to participate in research trials. In an effort to be more globally applicable, many current international ethical guidelines for informed consent in research on human subjects attempt to incorporate community in the informed consent process. This book explains how these attempts encounter two primary problems: (1) they fail to adequately acknowledge the importance community has for many people in less developed countries; and (2) they fail to attend to the constraints to autonomy that oftentimes become magnified once community is involved in the informed consent process. The reason for these shortcomings can be traced to the current account of autonomy reflected in international informed consent guidelines, which is here referred to as the traditional account of autonomy. Although traditional autonomy can account for what this book defines as external constraints to autonomy, it is unequipped to recognize the internal constraints which arise in the medical context. In order to adequately recognize the importance of community in autonomy and to attend to internal constraints to autonomy, it is essential to adopt an account of relational autonomy. Using such a relational autonomy account, the book provides a set of minimally sufficient ethical conditions that can assist policy makers in revising international informed consent guidelines in research on human subjects, so that these guidelines better attend to community involvement in the informed consent process. To demonstrate how these conditions might be used, the book also presents examples of possible revisions to the CIOMS Ethical Guidelines, one of the leading international ethical guidelines for research on human subjects.

    • Human-computer interaction
      June 2011

      Simulation-based Medical Training

      A User-Centred Design Perspective

      by Author(s): Erik Lövquist

      This volume explores the development process of a Virtual Reality (VR) and web-based medical training system from a user-centred perspective. It highlights the importance of user participation in this context by analysing two case studies concerned with the development of a VR and web-based medical training system for Spinal Anaesthesia.It illustrates the relationship between user participation and the development process of a VR and web-based medical training system. User groups, along with their input and degrees of participation and influence, are classified. It shows how a democratic arrangement between users and developers is beneficial and maybe even mandatory in order to utilise the users’ guidance efficiently. In this arrangement, the use of prototypes is instrumental in bridging the expertise and knowledge gap between users and developers.Reading this volume may aid other research teams developing VR and web-based medical training systems in deciding if, why and how to involve relevant user groups in the overall development process.

    • Physiology
      September 2013

      Vascular Function and Structure in the Rat Aorta

      by Author(s): Keith Wan Kee Ng

      One of the inevitable consequences of ageing is the progressive widening of pulse pressure resulting from stiffening of large arteries. While a large body of literature has been devoted to understanding blood pressure, a parameter proven to be predictive of cardiovascular health, very few books are devoted to explaining arterial stiffening, how it worsens, and why is it important for physicians to consider arterial stiffening when treating resistant hypertension. This book fills this gap. The fundamental purpose of this book is to systematically explain the pathophysiology behind arterial stiffness, to relate arterial stiffness with high blood pressure, and also to draw insights into the management of arterial stiffness from the current clinical and experimental research evidence in the field.Set out systematically, the book provides a readable and concise introduction to arterial stiffness and progressively moves into explaining more complex theoretical and experimental developments in the area. The book is designed such that each chapter largely answers a particular scientific question – covering the most up-to-date research information, investigations, and summaries and conclusions relating to the initial question. Future directions and research opportunities in the field are also covered.The book covers the most recent in vivo assessments of aortic stiffness in different phenotypes by measuring local haemodynamic parameters, pulse wave velocity, and pulse pressure amplification. Furthermore, the book relates ex vivo arterial structural properties and explains how they are relevant to arterial stiffness measurement, while also analysing recent pharmacological treatments of hypertension and assessing if these treatments have any effect on arterial stiffness in addition to treating blood pressure alone. Finally, the text offers a summary and appraisal of the methodologies used in experimental quantification of arterial stiffness.

    • Biology, life sciences
      October 2014

      Medical and Applied Malacology Crossing Boundaries

      Integrative Approaches to Malacology

      by Editor(s): Ana Rita de Toledo Piza, Lenita de Freitas Tallarico, Gisele Orlandi Introíni and Sonia Barbosa dos Santos

      This book provides an overview of the XI International Congress on Medical and Applied Malacology: “Crossing Boundaries: Integrative Approaches to Malacology”. The event was held at the State University of Rio de Janeiro between the 25th and 29th of September 2012.A number of the plenary lecturers from the conference were invited to contribute their papers to these proceedings, as were speakers whose papers were eligible for student awards. The volume contains articles on bioprospecting methods; medical malacology; aquaculture; biomonitoring; alien species; reproductive and developmental biology; interdisciplinary teaching and education; and trends in malacological research.The information contained here will convey to the general public the importance of mollusks to human and animal health, as well as their applications in various areas of knowledge.

    • Medical research
      January 2015

      Community, Autonomy and Informed Consent

      Revisiting the Philosophical Foundation for Informed Consent in International Research

      by Author(s): Pamela J. Lomelino

      In using the example of informed consent guidelines for international research on human subjects, this book demonstrates one of the many useful ways that philosophy can be used to move from theory to praxis by providing a general picture of how a philosophical analysis of underlying concepts can affect the way that public policy is framed; the ways that such policies are exclusionary; and a general methodology for remedying injustices in public policy and practice once they have been identified.With diseases, such as AIDS, reaching epidemic proportions in less developed countries, medical research on human subjects in these areas is on the rise. Current international guidelines for research on human subjects stress the importance of informed consent, which is meant to ensure that people freely choose whether to participate in research trials. In an effort to be more globally applicable, many current international ethical guidelines for informed consent in research on human subjects attempt to incorporate community in the informed consent process. This book explains how these attempts encounter two primary problems: (1) they fail to adequately acknowledge the importance community has for many people in less developed countries; and (2) they fail to attend to the constraints to autonomy that oftentimes become magnified once community is involved in the informed consent process. The reason for these shortcomings can be traced to the current account of autonomy reflected in international informed consent guidelines, which is here referred to as the traditional account of autonomy. Although traditional autonomy can account for what this book defines as external constraints to autonomy, it is unequipped to recognize the internal constraints which arise in the medical context. In order to adequately recognize the importance of community in autonomy and to attend to internal constraints to autonomy, it is essential to adopt an account of relational autonomy. Using such a relational autonomy account, the book provides a set of minimally sufficient ethical conditions that can assist policy makers in revising international informed consent guidelines in research on human subjects, so that these guidelines better attend to community involvement in the informed consent process. To demonstrate how these conditions might be used, the book also presents examples of possible revisions to the CIOMS Ethical Guidelines, one of the leading international ethical guidelines for research on human subjects.

    • Medical research
      May 2009

      Research Methods for Health Care Practice

      by Griffiths, Frances

      A step-by-step guide to planning and carrying out research to improve professional practice.

    • Medical research
      May 2009

      Service-User Research in Health and Social Care

      by McLaughlin, Hugh

      The first book to tackle the importance of service user involvement in health and social welfare

    • Medical research
      December 2009

      Introductory Statistics for Health and Nursing Using SPSS

      by Marston, Louise

      Specifically written for students in the health sciences, this book covers simple statistical concepts and then shows how to analyse data using SPSS.

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